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  1. The social consequences of COVID-19 pandemic are universally known. In particular, the pediatric population is dealing with a radical lifestyle change. For some risk categories, such as overweight or obese chi...

    Authors: M. Valenzise, F. D’Amico, U. Cucinotta, C. Lugarà, G. Zirilli, A. Zema, M. Wasniewska and G. B. Pajno

    Citation: Italian Journal of Pediatrics 2021 47:209

    Content type: Research

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  2. Heterozygous variants in CNTNAP2 have been implicated in a wide range of neurological phenotypes, including intellectual disability (ID), epilepsy, autistic spectrum disorder (ASD), and impaired language. However...

    Authors: Marcello Scala, Midas Anijs, Roberta Battini, Francesca Madia, Valeria Capra, Paolo Scudieri, Alberto Verrotti, Federico Zara, Carlo Minetti, Sonja C. Vernes and Pasquale Striano

    Citation: Italian Journal of Pediatrics 2021 47:208

    Content type: Case report

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  3. Idiopathic hemoperitoneum in the newborn is an entity very rarely encountered in clinical practice.

    Authors: Salatto Alessia, Indrio Flavia, Campanella Vittoria, Maggipinto Cosetta, Cocomazzi Raffaella, Canale Francesco, Nobili Maria, Maffei Gianfranco and Bartoli Fabio

    Citation: Italian Journal of Pediatrics 2021 47:207

    Content type: Case report

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  4. The breastfeeding technique is explained positioning, attachment, and suckling during breastfeeding. Ineffective breast feeding technique is one of the factors leading to premature discontinuation of breastfee...

    Authors: Boko Loka Safayi, Nega Tezera Assimamaw and Destaye Guadie Kassie

    Citation: Italian Journal of Pediatrics 2021 47:206

    Content type: Research

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  5. Malnutrition is very common in HIV-infected individuals. Even though data from different settings are necessary to tackle it, pieces of evidence are limited especially in the case of the nutritional status of ...

    Authors: Chalie Marew Tiruneh, Belete Gelaw Walle, Tigabu Desie Emiru, Nigusie Selomon Tibebu, Moges Wubneh Abate, Adane Birhanu Nigat, Amsalu Belete, Eyasu Alem, Tadele Lankrew and Kirubel Eshetu

    Citation: Italian Journal of Pediatrics 2021 47:205

    Content type: Research

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  6. The COVID-19 pandemic and the subsequent national lockdowns, school closures and distance learning may have had both negative and positive effects on physical and mental health of children.

    Authors: Marina Picca, Paola Manzoni, Gregorio Paolo Milani, Susanna Mantovani, Claudio Cravidi, Danila Mariani, Angela Mezzopane, Roberto Marinello, Chiara Bove, Paolo Ferri, Marina Macchi and Carlo Agostoni

    Citation: Italian Journal of Pediatrics 2021 47:203

    Content type: Research

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  7. Neonatal hypoglycemia is a common disorder especially in at-risk infants and it can be associated with poor long-term neurological outcomes. Several therapeutic interventions are suggested, from the implementa...

    Authors: Fabio Meneghin, Martina Manzalini, Miriam Acunzo, Irene Daniele, Petrina Bastrenta, Francesca Castoldi, Francesco Cavigioli, Gian Vincenzo Zuccotti and Gianluca Lista

    Citation: Italian Journal of Pediatrics 2021 47:201

    Content type: Research

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  8. Respiratory syncytial virus (RSV) is the leading global cause of respiratory infections in infants and the second most frequent cause of death during the first year of life. This highly contagious seasonal vir...

    Authors: Chiara Azzari, Eugenio Baraldi, Paolo Bonanni, Elena Bozzola, Alessandra Coscia, Marcello Lanari, Paolo Manzoni, Teresa Mazzone, Fabrizio Sandri, Giovanni Checcucci Lisi, Salvatore Parisi, Giorgio Piacentini and Fabio Mosca

    Citation: Italian Journal of Pediatrics 2021 47:198

    Content type: Review

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  9. Hypertrophic cardiomyopathy (HCM) in neonates is a rare and heterogeneous disorder. HCM accounts for 25 to 40% of all pediatric cardiomyopathy cases and the highest incidence in pediatric population is reporte...

    Authors: Alessia Claudia Codazzi, Rosario Ippolito, Cecilia Novara, Enrico Tondina, Rosa Maria Cerbo and Chryssoula Tzialla

    Citation: Italian Journal of Pediatrics 2021 47:197

    Content type: Case report

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  10. Ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome, also known as Hay-Wells syndrome, is a rare genetic syndrome with ectodermal dysplasia. About 100 patients have been reported to date. It is ...

    Authors: Gregorio Serra, Vincenzo Antona, Mario Giuffré, Federica Li Pomi, Lucia Lo Scalzo, Ettore Piro, Ingrid Anne Mandy Schierz and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2021 47:196

    Content type: Case report

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  11. Solar urticaria represents an uncomfortable form of chronic inducible urticaria. First and second-line treatments are ineffective in some patients, leading to an impairment in their quality of life. Omalizumab...

    Authors: Mauro Iannelli, Stefano Passanisi, Giuseppe Crisafulli, Stefania Arasi, Lucia Caminiti, Giuseppina Zirilli and Giovanni B. Pajno

    Citation: Italian Journal of Pediatrics 2021 47:195

    Content type: Case report

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  12. Cases of foreign body aspiration in children may be encountered in emergency departments. A suggestive history is important in diagnosing aspirated foreign body owing to the difficulty in making a diagnosis on...

    Authors: Nader A. Fasseeh, Osama A. Elagamy, Alaa H. Gaafar, Heba M. Reyad, Mohamed S. Abougabal, Doaa A. Heiba and Ahmad Kantar

    Citation: Italian Journal of Pediatrics 2021 47:194

    Content type: Research

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  13. The locations where children get exposed to SARS-CoV-2 infection and their contribution in spreading the infection are still not fully understood. Aim of the article is to verify the most frequent reasons for ...

    Authors: Mauro Calvani, Giulia Cantiello, Maria Cavani, Eleonora Lacorte, Bruno Mariani, Valentina Panetta, Pasquale Parisi, Gabriella Parisi, Federica Roccabella, Paola Silvestri and Nicola Vanacore

    Citation: Italian Journal of Pediatrics 2021 47:193

    Content type: Research

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  14. Vaccine hesitancy is a global problem, carrying significant health risks for extremely vulnerable population as that of preterm infants. Social media are emerging as significant tools for public health promoti...

    Authors: Antonio Di Mauro, Federica Di Mauro, Chiara Greco, Orazio Valerio Giannico, Francesca Maria Grosso, Maria Elisabetta Baldassarre, Manuela Capozza, Federico Schettini, Pasquale Stefanizzi and Nicola Laforgia

    Citation: Italian Journal of Pediatrics 2021 47:190

    Content type: Research

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  15. Congenital nasal pyriform aperture stenosis (CNPAS) is a rare condition that may occur alone or as part of a multi-formative syndrome. Management remains difficult. There is no specific treatment protocol. Tra...

    Authors: Emanuela Sitzia, Sara Santarsiero, Filippo Maria Tucci, Giovanni De Vincentiis, Angela Galeotti and Paola Festa

    Citation: Italian Journal of Pediatrics 2021 47:189

    Content type: Case report

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  16. 15q26 deletion is a relatively rare chromosomal disorder, and it is described only in few cases. Patients with this aberration show many signs and symptoms, particularly pre- and postnatal growth restriction, ...

    Authors: Yahya Benbouchta, Nicole De Leeuw, Saadia Amasdl, Aziza Sbiti, Dominique Smeets, Khalid Sadki and Abdelaziz Sefiani

    Citation: Italian Journal of Pediatrics 2021 47:188

    Content type: Case report

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  17. Although it is known that unbound bilirubin can enter the brain, there is little evidence of its association with the development of acute bilirubin encephalopathy. Here, we investigated this potential relatio...

    Authors: Yiyi Ding, Shuo Wang, Rui Guo, Aizhen Zhang and Yufang Zhu

    Citation: Italian Journal of Pediatrics 2021 47:187

    Content type: Research

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  18. Neonatal mortality is a major global public health problem. Ethiopia is among seven countries that comprise 50 % of global neonatal mortality. Evidence on neonatal mortality in referred neonates is essential f...

    Authors: Alex Yeshaneh, Bizuayehu Tadele, Bogale Dessalew, Mulunesh Alemayehu, Awraris Wolde, Addisu Adane, Solomon Shitu, Haimanot Abebe and Daniel Adane

    Citation: Italian Journal of Pediatrics 2021 47:186

    Content type: Research

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  19. Authors: Erica Rosina, Berardo Rinaldi, Rosamaria Silipigni, Luca Bergamaschi, Giovanna Gattuso, Stefano Signoroni, Silvana Guerneri, Alessandra Carnevali, Paola Giovanna Marchisio and Donatella Milani

    Citation: Italian Journal of Pediatrics 2021 47:185

    Content type: Correction

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    The original article was published in Italian Journal of Pediatrics 2021 47:31

  20. Malnutrition is a multifactorial pathology in which genetic, epigenetic, cultural, environmental, socio-economic factors interact with each other. The impact that this disease has on the health of children wor...

    Authors: Federica Maria Tripoli, Salvatore Accomando, Simona La Placa, Andrea Pietravalle, Giovanni Putoto, Giovanni Corsello and Mario Giuffrè

    Citation: Italian Journal of Pediatrics 2021 47:184

    Content type: Research

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  21. Physicians play a key role in driving vaccine acceptance and their recommendations are crucial to address vaccine hesitancy. The aim of the study was to assess knowledge, awareness and attitude of Italian Pedi...

    Authors: Elisabetta Del Duca, Loredana Chini, Simona Graziani, Mayla Sgrulletti and Viviana Moschese

    Citation: Italian Journal of Pediatrics 2021 47:183

    Content type: Research

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  22. To determine the prevalence of surgical site infections (SSIs) in neonatal congenital heart disease patients undergoing delayed sternal closure (DSC) and evaluate risk factors for SSI.

    Authors: Yuzhong Yang, Jie Wang, Lina Cai, Wei Peng and Xuming Mo

    Citation: Italian Journal of Pediatrics 2021 47:182

    Content type: Research

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  23. The Neurological involvement is the most common extra-renal complication of Shiga toxin-producing E. coli-hemolytic uremic syndrome (HUS) or typical HUS. On brain magnetic resonance examination, main neurological...

    Authors: Luisa Santangelo, Giuseppe Stefano Netti, Diletta Domenica Torres, Giovanni Piscopo, Vincenza Carbone, Luciana Losito, Leonardo Milella, Maria Luigia Lasorella, Pasquale Conti, Delio Gagliardi, Maria Chironna, Federica Spadaccino, Elena Bresin, Antonio Trabacca, Elena Ranieri and Mario Giordano

    Citation: Italian Journal of Pediatrics 2021 47:181

    Content type: Case report

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  24. In healthy adolescents, delayed pubarche is generally a benign condition that is caused by a physiological discrepancy between gonadarche and adrenarche. In presence of other clinical signs and symptoms, delay...

    Authors: Francesco Baldo, Egidio Barbi and Gianluca Tornese

    Citation: Italian Journal of Pediatrics 2021 47:180

    Content type: Review

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  25. Acute hematogenous osteomyelitis (AHOM) is an insidious infection of the bone that more frequently affects young males. The etiology, mainly bacterial, is often related to the patient’s age, but it is frequent...

    Authors: Andrzej Krzysztofiak, Elena Chiappini, Elisabetta Venturini, Livia Gargiullo, Marco Roversi, Carlotta Montagnani, Elena Bozzola, Sara Chiurchiu, Davide Vecchio, Elio Castagnola, Paolo Tomà, Gian Maria Rossolini, Renato Maria Toniolo, Susanna Esposito, Marco Cirillo, Fabio Cardinale…

    Citation: Italian Journal of Pediatrics 2021 47:179

    Content type: Review

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  26. Immune thrombocytopenic purpura (ITP) is an acquired complex autoimmune thrombocytopenia. Uncontrolled cellular immune response is one of the key triggers for the loss of immune tolerance in ITP patients. The ...

    Authors: Ahlam M. Ismail, Aliaa M. Higazi, Hanan M. Nomeir and Naglaa M. Farag

    Citation: Italian Journal of Pediatrics 2021 47:178

    Content type: Research

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  27. To date, information on COVID-19 long-term post-recovery sequelae in children and adolescents remains scarce. A retrospective descriptive cohort study was performed by collecting data on 92 patients (age ≤ 18 ...

    Authors: Liene Smane, Ieva Roge, Zanda Pucuka and Jana Pavare

    Citation: Italian Journal of Pediatrics 2021 47:177

    Content type: Letter to the Editor

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  28. The Post-traumatic Stress Disorder (PTSD) is a group of persistent psychological and physiological symptoms due to a traumatic, severe, event. Only few studies focused on the effects of Covid-19 on psychosocia...

    Authors: C. Carducci, N. Rapini, A. Deodati, V. Pampanini, S. Cianfarani and R. Schiaffini

    Citation: Italian Journal of Pediatrics 2021 47:176

    Content type: Research

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  29. Congenital chylothorax (CC) is a rare but potentially life-threatening condition in newborns. It is defined as an accumulation of chyle in the pleural cavity. The few publications regarding medical management ...

    Authors: Michaela Höck, Alexander Höller, Marlene Hammerl, Karina Wechselberger, Jakob Krösslhuber, Ursula Kiechl-Kohlendorfer, Sabine Scholl-Bürgi and Daniela Karall

    Citation: Italian Journal of Pediatrics 2021 47:175

    Content type: Research

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  30. Stunting was a significant public health problem for under-five in developing countries including Ethiopia. Globally, it was estimated 21.9% or 149 million (81.7 million in Asia and 58.8 million in Africa) und...

    Authors: Ayechew Ademas, Metadel Adane, Awoke Keleb, Gete Berihun and Getu Tesfaw

    Citation: Italian Journal of Pediatrics 2021 47:174

    Content type: Research

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  31. Child malnutrition is still a concern in marginalized groups of populations, such as immigrants living in very low socio-economic conditions. Roma children are within the most hard-to-reach populations, suscep...

    Authors: Rosaria Giampaolo, Rosaria Marotta, Francesco Saverio Biagiarelli, Antonella Zampa, Stefania Moramarco and Ersilia Buonomo

    Citation: Italian Journal of Pediatrics 2021 47:173

    Content type: Research

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  32. Anemia, the most common micro-nutrient deficiency disorder, is the world’s second leading cause of morbidity and morbidity, affecting 24.8% of the population, of which 47.4% are under-five children. The preval...

    Authors: Yoseph Merkeb Alamneh, Tadesse Yirga Akalu, Abtie Abebaw Shiferaw and Aytenew Atnaf

    Citation: Italian Journal of Pediatrics 2021 47:172

    Content type: Research

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  33. Fake news on children’s and adolescent health are spreading. Internet availability and decreasing costs of media devices are contributing to an easy access to technology by families. Public health organization...

    Authors: Elena Bozzola, Anna Maria Staiano, Giulia Spina, Nicola Zamperini, Francesco Marino, Marco Roversi and Giovanni Corsello

    Citation: Italian Journal of Pediatrics 2021 47:171

    Content type: Research

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  34. The Children’s Sleep Habits Questionnaire (CSHQ) is a parent-report questionnaire used to examine sleep behavior in children. Linguistic adaptation of CSHQ into several languages and/or psychometric analysis o...

    Authors: Melissa Borrelli, Iris Scala, Paola Festa, Dario Bruzzese, Ambrosina Michelotti, Elena Cantone, Adele Corcione, Martina Fragnito, Vincenzo Miranda and Francesca Santamaria

    Citation: Italian Journal of Pediatrics 2021 47:170

    Content type: Letter to the Editor

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  35. Staphylococcal Scalded Skin Syndrome (SSSS) is caused by a special type of Staphylococcus aureus (S.aureus) which can produce exfoliative toxins. The generalized SSSS is recommended to be admitted and treated wit...

    Authors: Tao Yang, Jiangyi Wang, Junya Cao, Xinyue Zhang, Yun Lai, Longnian Li, Xiaoying Ye and Cong You

    Citation: Italian Journal of Pediatrics 2021 47:169

    Content type: Research

    Published on:

  36. Cystic fibrosis (CF) is a multisystem disorder, caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. These cause a reduced secretion of chloride, a marked absorption of sodium and, th...

    Authors: Vito Terlizzi, Eleonora Masi, Michela Francalanci, Giovanni Taccetti and Diletta Innocenti

    Citation: Italian Journal of Pediatrics 2021 47:168

    Content type: Review

    Published on:

  37. The use of once daily dosing of aminoglycosides in pediatrics is increasing but studies on dose optimization targeting the pediatric population are limited. This study aimed to derive a population pharmacokine...

    Authors: Ragia H. Ghoneim, Abrar K. Thabit, Manar O. Lashkar and Ahmed S. Ali

    Citation: Italian Journal of Pediatrics 2021 47:167

    Content type: Research

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  38. Lack of exclusive breastfeeding during the first 6 months of infant life contributes to childhood morbidity and mortality. This study aimed to investigate the association of exclusive breastfeeding and childho...

    Authors: Tesfahun Mulatu, Nigus Bililign Yimer, Birhan Alemnew, Melese Linger and Misgan Legesse Liben

    Citation: Italian Journal of Pediatrics 2021 47:166

    Content type: Research

    Published on:

  39. Grip strength is an essential component of physical fitness. The objective of this study was to develop normative handgrip strength data for Iranian healthy boys and girls comparing their handgrip strength wit...

    Authors: Sajjad Rostamzadeh, Mahnaz Saremi, Alireza Abouhossein, Shahram Vosoughi and Johan F. M. Molenbroek

    Citation: Italian Journal of Pediatrics 2021 47:164

    Content type: Research

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  40. The objective of the present article is to highlight the need for attention to Quality of Life of patients with Sickle Cell Disease living in Italy. The transformation of sickle cell disease from a severe life...

    Authors: Raffaella Colombatti, Maddalena Casale and Giovanna Russo

    Citation: Italian Journal of Pediatrics 2021 47:163

    Content type: Commentary

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  41. In Ethiopia, stunting is the most common form of undernutriton. Identifying the determinants of severe stunting among children is crucial for public health interventions to improve child health. Therefore, thi...

    Authors: Amare Muche and Reta Dewau

    Citation: Italian Journal of Pediatrics 2021 47:161

    Content type: Research

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  42. Wiedemann-Rautenstrauch syndrome (WRS) is a rare autosomal recessive neonatal progeroid disorder characterized by prenatal and postnatal growth retardation, short stature, a progeroid appearance, hypotonia, an...

    Authors: Shao-Wen Wu, Lin Li, Fan Feng, Li Wang, Yuan-Yuan Kong, Xiao-Wei Liu and Chenghong Yin

    Citation: Italian Journal of Pediatrics 2021 47:160

    Content type: Case report

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