Table 1 Clinical features of neonates born to mothers with perinatal confirmed SARS-CoV-2 infection
From: Novel Coronavirus disease (COVID-19) in newborns and infants: what we know so far
All | Dong et al. [30] | Chen et al. [32] | Li et al. [33] | Wang et al. [34] | Zhu et al. [35] | Chen et al. [36] | Liu et al. [37] | Zeng et al. [38] | Piersigilli et al. (unpublished) | |
|---|---|---|---|---|---|---|---|---|---|---|
Pregnant women | 69 | 1 | 9 | 1 | 1 | 9 (1 was a mother of twins) | 4 | 10 | 33 | 1 |
Caesarean section | 53/69 (76.8%) | 1 | 9/9 | 1 | 1 | 7/9 | 3/4 | 10/10 | 26/33 | 1 |
Positive maternal test (SARS-CoV-2 quantitative RT-PCR on samples from the respiratory tract) | 68/69 (98.6%) | 1 | 9/9 | 1 | 1 | 8/9 * | 4/4 | 10/10 | 33/33 | 1 |
Median maternal age, years (range) | 30 (22–40) | 29 | 28 (26–40) | 30 | 28 | 30 (25–35) | 29.5 (23–34) | 30.5 (22–36) | NA | 37 |
Median gestational age (GA) on admission, weeks (range) | 36 (26–39) | 38 | 37 (36–39) | 35 | 30 | 34 (31–39) | 37.5 (37–39) | 35.5 (32–38) | NA | 26 |
Median onset of maternal symptoms to delivery, days (range) | 2.5 (0–26) | 26 | 3 (1–7) | 2 | 6 | 2.5 (0–6) | NA | NA | NA | 2 |
Maternal fever on admission | 37/69 (53.6%) | 1 | 7/9 | 1 | 1 | 8/10 | 3/4 | 8/10 | 8/33 | 0 |
Newborns | 70 | 1 | 9 | 1 | 1 | 10 | 4 | 10 | 33 | 1 |
Positive cord blood samples | 0 | 0 ** | 0/6 | 0 | 0 | NA | NA | NA | NA | NA |
Positive neonatal throat swab samples | 4/63 tested | 0 ** | 0/6 | 0 | 0 | 0/9;1 not tested | 0/3; 1 not tested | 0/10 | 3/33 | 1 |
Positive breastmilk samples | 0 | 0 | 0/6 | 0 | 0 | 0/9; 1 not tested | 0/3; 1 not tested | 0/10 | NA | 0 |
Low birthweight (< 2500 g) | 14/70 (20%) | 0 | 2/9 | NA | 1 | 7/10 | 0 | NA | 3/33 | 1 |
Premature delivery | 24/70 (34.3%) | 0 | 4/9 | 1 | 1 | 6/10 | 1 | 6/10 | 4/33 | 1 |
Intrauterine foetal distress | 15/69 (22%) + 1 stillbirth | 0 | 0 | 1 | 6/10 | 1/4 | 3/10 + 1 stillbirth | 0 | 2/33 | 2/9 |
Premature rupture of membranes | 6/70 (8.6%) | 0 | 2/9 | 0 | 0 | 3/10 | 0 | 1/10 | 3/33 | 0 |