Fig. 5

The distribution of different causative genes in different renal biopsy types. A total of 42 children were detected with causative mutations and completed renal biopsies. Inner segments represent the numbers and fractions of renal biopsy types, specifically as follows: MCD, 13 out of 42; FSGS, 18 out of 42; Other1, 11 out of 42. Outer segments represent for each renal biopsy group the relative fraction of different causative mutations. We described the 5 specific causative mutations that accounted for a large share or occurred frequently, others are grouped in other2. The distribution is as follows: WT1 (1 out of 42), COL4A3 (1 out of 42), COL4A5 (1 out of 42), NPHS1 (2 out of 42) and other causative mutations (8 out of 42) were detected in MCD group. WT1 (1 out of 42), COL4A5 (2 out of 42), NPHS1 (1 out of 42), NPHS2 (2 out of 42) and other causative mutations (12 out of 42) were detected in FSGS group. COL4A3 (1 out of 42), COL4A5 (5 out of 42) and other causative mutations (5 out of 42) were detected in other renal pathological group. Other1: Alport syndrome, various glomerulonephritis, Membranous nephropathy. Other2: Other causative genes detected in patients with different pathological groups