Fig. 6

Flowchart for the selection of genetic testing strategies for SRNS patients. The first strategy was used in children who chose the panel first with 96 in total, 50 of whom had causative mutations, and 46 had negative results; all of the 46 panel-negative children chose to have further WES tests, and 4 additional causative mutations were detected in the end. Another group included 236 children who chose WES first, 41 of whom had causative mutations, and 195 had negative results. Of the 195 WES-negative children, 117 chose to be further tested for WGS, and finally, 5 additional causative mutations were detected